Chinese Journal of Tissue Engineering Research ›› 2014, Vol. 18 ›› Issue (30): 4757-4763.doi: 10.3969/j.issn.2095-4344.2014.30.001
Feng Xin-min, Wang Jing-cheng, Zhang Liang, Tao Yu-ping, Yang Jian-dong, Cai Jun, Zhang Sheng-fei, Huang Ji-jun
Revised:
2014-06-10
Online:
2014-07-16
Published:
2014-08-08
Contact:
Zhang Liang, Attending physician, Lecturer, Northern Jiangsu People’s Hospital, Yangzhou 225001, Jiangsu Province, China
About author:
Feng Xin-min, Master, Chief physician, Associate professor, Northern Jiangsu People’s Hospital, Yangzhou 225001, Jiangsu Province, China
Supported by:
grants from the Development Center for Medical Science and Technology, Ministry of Health, No. W2012ZT14; Natural Science Foundation of Jiangsu Province for Youths, No. 20140496 BK; Program for the Talents in Science and Education of Yangzhou, China
CLC Number:
Feng Xin-min, Wang Jing-cheng, Zhang Liang, Tao Yu-ping, Yang Jian-dong, Cai Jun, Zhang Sheng-fei, Huang Ji-jun. Application of high viscosity bone cement in thoracolumbar osteoporotic compression fractures[J]. Chinese Journal of Tissue Engineering Research, 2014, 18(30): 4757-4763.
2.1 参与者数量分析 20例患者均顺利完成手术,完成1年以上随访,按意向性处理分析,20例均进入结果分析。 2.2 伤椎椎体前缘高度恢复 治疗后患者伤椎椎体前缘高度得到明显改善,由治疗前的(53.6±10.5)%到治疗后 3 d的(10.3±4.2)%和治疗后1年的(11.5±3.7)%,治疗前后椎体高度比较差异有显著性意义(P < 0.05),治疗后3 d和治疗后1年椎体高度比较差异无显著性意义(P > 0.05),见表1。 2.3 腰背部疼痛及功能恢复情况 术后腰背部疼痛明显缓解或消失,腰背部功能明显改善,生活质量评分得到明显提高,治疗后3 d及1年的目测类比评分、ODI评分明显低于治疗前(P < 0.05),治疗后3 d和治疗后1年的目测类比评分、ODI评分比较差异无显著性意义(P > 0.05)。治疗后3 d及1年的SF-36物理评分及心理评分均高于术前(P < 0.05),治疗后3 d和治疗后1年的SF-36物理评分及心理评分比较差异无显著性意义(P > 0.05),见表1。治疗后神经功能均正常为Frankle E级,与治疗前相同。 2.4 并发症及不良反应 所有手术均顺利完成,每个椎体注射骨水泥量2-5 mL,术中血压及血氧饱和度均正常。治疗后随访12-18个月,平均14.5个月。术后复查X射线及CT见骨水泥弥散良好,只有1例发生椎管内少量骨水泥渗漏及1例椎体前方渗漏,但无任何临床症状,无骨水泥毒性或过敏反应、肺栓塞、感染和神经损伤等并发症发生。随访期间无新发骨折。"
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